Database

LLS ROWIAK LaserLabSolutions GmbH

Solution provided
Technology
Supplier identity
General description

The core expertise of LLS ROWIAK LaserLabSolutions GmbH lies in the development and production of innovative laser systems for the non-invasive processing of tissues and materials and for use in laser surgery. For the Life Sciences sector, the company offers solutions for automated cell monitoring, imaging and cell manipulation, as well as for cell, tissue and material processing using laser microtomy or multiphoton manipulation combined with imaging.

Type of Supplier
Lab Equipment Supplies Provider
Region
State of Lower Saxony, DE
Regional access broker
  • Annika Buchholz, BiomeTI e.V.
Activity description
The 3 top equipments available

LLS ROWIAK LaserLabSolutions GmbH has established the innovative power of Femtosecond Laser Technology in Life Sciences Market. LLS ROWIAK not only offers high quality laser instruments for tissue processing and cell manipulation, but also provides services in tissue and material sample preparation, and is your expert partner for laser application research.

The TissueSurgeon is a multi-purpose system designed for non-contact precise sectioning for histology, micro-structuring and imaging of biological tissue and various non-metal materials with the help of photons instead of (steel-) blades. It is suitable for processing biological tissue as well as materials, such as ceramics, polymers and resins. The TissueSurgeon overcomes the limitations of common methods like microtomy, ground sections or laser-microdissection (LMD). Based on Femtosecond Laser Technology, it can be used for three-dimensional sectioning or gentle extraction of samples and materials for further analysis. For navigation and imaging of samples, the TissueSurgeon can be equipped with Optical Coherence Tomography (OCT) and Multiphoton Microscopy (MPM). This provides great flexibility and enables novel approaches.

CellSurgeon is a laser dissection and multiphoton imaging system which enables precise, contact-free 3D-nanodissection and imaging of cells and subcellular structures. CellSurgeon can be used in living cells for studies of cell dynamics and biomechanics. Selective manipulation of cell organelles makes it possible to assess an impact on specific cellular processes. Furthermore, CellSurgeon is suitable for optoporation*, a novel highly effective method of cell transfection. Experiments of accurate cutting in living small organisms with subsequent time-lapse recordings in 3D can easily be performed by means of CellSurgeon.

Know-how, expertise available

interaction of tissue with ultrashort pulse lasers

laseb based imaging

lased tissue and material preparation for histological, microscopic and biochemical analysis

Possibilities of partnership

Research and Development projects in bone, dental or cardiological research including imaging methods and tissue preparation

Services provided

 

 

Terms of availability for SMEs

Laser microtomy for histology and material quality and failure analysis

  • Sectioning of biological tissue and of non-decalcified hard tissue
  • Cutting and microstructuring of biomaterials, polymers and hard materials

Manipulation by Nanodissection

  • Nanosurgery within cells and sub-cellular structures
  • Ablation of cell organelles
  • Optical perforation of cell membranes

Development and Consulting

  • Development of new methods and systems for the use of femtosecond laser sytems in life sciences, medicine and material processing - from proof of principle o prototyping
  • Integration of laser cutting tools into existing imaging systems
  • Development of new applications
  • Development of new methods for the preparation of specimens
  • Costumizing of our laser systems for your application
  • Technical advice and concept development for femtosecond laser applications in tissue and materials processing
  • Feasibility studies
Training and Staff possibilities
Yes
Training and Staff exchange terms and conditions

For students with background in physics, engineering, IT, material sciences and biophysics / biology / biotechnology we frequently offer internship positions and jobs as student assistants.

Contact information
Name
Birgitta
Surname
Dr. Stolze
Function
Managing Director
Phone number
+49 511 277 2976
Address
Garbsener Landstraße 10
30419  Hannover
Germany