Database

ExpreS²ion Biotechnologies

Solution provided
Technology
Supplier identity
General description

ExpreS²ion Biotechnologies (ExpreS²ion) is a leader in recombinant protein production with Drosophila S2 cells. Our proprietary platform is an alternative for dead-end and cost-sensitive protein projects, has excellent scalability, versatility of production processes and regulatory friendliness. We provide custom GLP protein production, protein variant screening and process development, with a focus on recombinant vaccines. Licenses to the platform are available

Type of Supplier
Service Provider - CMO / CRO
Sector of activity
  • Biomanufacturing
  • Drug Discovery / Research & Development
  • Protein Therapeutics
  • Vaccines
Region
Denmark, DK
Regional access broker
  • Sophie Labrosse, Biopeople
Activity description
The 3 top equipments available
  • Äkta Avant 25,
  • SOA Bioreactor park including SUB,
  • Nuclear counter NC3000.
Know-how, expertise available

Complex and challenging protein production in a proprietary Drosophila S2 cells system.

Possibilities of partnership
  • Collaborations with Academic teams on Vaccine development: ExpreS²ion
  • Collaboration with Copenhagen University for establishment of cell lines producing a malaria protein being used in development of a placental malaria vaccine.  For this project, ExpreS²ion has produced over 30 protein variants for Copenhagen University to screen. The process for production of the selected protein variant is being developed by ExpreS²ion, and will be transferred to a CMO for cGMP production. The funding for this work comes from HTF (DK) and FP7 (EU).
  • Collaboration with the Jenner Institute at Oxford University for production of a malaria protein being developed for a blood stage malaria vaccine. ExpreS²ion is responsible for all protein production and process development aspects.
  • Eurostars projects: Collaboration with the University of Copenhagen and the company Mucosis.
  • Various collaborations with companies with cutting edge technologies, such as Refine, Merck Millipore and others. 
Services provided

We offer the following services, based on our proprietary protein expression platform ExpreS²: vector and cell line development, up- and downstream process development, GLP custom protein production, process transfer to cGMP, CMC consulting within S2 expression. 

Terms of availability for SMEs

We work exclusively within S2 cells systems.

Targeted countries

Europe, NA, Japan, BRIC

Market expertise
We operate globally.
Training and Staff possibilities
No
Training and Staff exchange terms and conditions

We offer training in handling our platform, in our laboratories, to our customers and collaborators. Depending on the experience, training takes one to two days.

Contact information
Name
Sancha
Surname
Salgueiro
Function
VP Business Development
Phone number
+45 41666121
Address
Agern alle 1
2970  Hørsholm
Denmark