Database

CiToxLAB Scantox A/S

Solution provided
Technology
Supplier identity
General description

The CiToxLAB Group offers a comprehensive range of pre-clinical services to meet the needs of pharmaceutical, biotechnology and chemical companies worldwide. CiToxLAB carries out studies in general and reproductive toxicology, carcinogenicity, bioanalysis, immunology and safety pharmacology. The group has special expertise in areas such as inhalation or intra-nasal toxicology, radiation safety (ARS), NHPs and minipigs.

Type of Supplier
Service Provider - CMO / CRO
Sector of activity
  • Animal models
  • Screening
  • Toxicology
Region
Denmark, DK
Regional access broker
  • Sophie Labrosse, Biopeople
Activity description
Know-how, expertise available

 

CiToxLAB carries out studies in general and reproductive toxicology, carcinogenicity, bioanalysis, immunology and safety pharmacology. The group has special expertise in areas such as inhalation or intra-nasal toxicology, radiation safety (ARS), NHPs and minipigs. Environmental studies are a further specialty including ecotoxicology and those related to REACH regulations.

 

Core battery toxicology:

Genotoxicity: mini-Ames, BlueScreen™, in vitro micronucleus

General  toxicology in all Rodent and Non-Rodent Species (including Minipig & NHPs)

In vivo lead optimization predictive toxicology

Toxicogenomics: Affymetrix

Safety  pharmacology including telemetry studies

Bioanalysis: LC-MS/MS, GC-MS/MS,  LC-ICP/MS

Formulation Analysis (HPLC)

Radiolabelled DMPK

Efficacy models

Reproductive toxicology, DART (including minipigs)

Carcinogenicity studies:  also in rasH2 and p53+/- mice

Physical chemistry

Medical Device biocompatibility testing

 

Leading edge expertise:

Juvenile studies (including minipigs)

Early toxicology: LeadScreen™ 14 days multi-endpoint in vivo toxicology screening

Non-human primates and transgenic rodents, including disease models

Biomarkers & Immunology: 10-color flow cytometer and Luminex

Tissue Cross Reactivity: human tissue bank

Bioanalysis & Immunogenicity by ELISA: custom designed

Biodistribution via qPCR

Image  analysis

Infusion

Inhalation

Dermal and Wound Healing

QSAR

 

Other key expertise:

Immunotoxicology

Ecotoxicology

Agrochemical testing

REACH certification and GLP services

devTOX™ & cardioTOX™

Radiation Safety (ARS)

Possibilities of partnership

 

CiToxLAB provides a comprehensive range of preclinical and specialty services from our facilities in France, Canada, Denmark and Hungary.  Our new group is a major global player in the preclinical outsourcing arena.

 

Our broad range of GLP (and non-GLP) nonclinical services combined with our >40 years of experience are at the service of our customers to meet the demands of today’s complex global marketplace. We can provide you with accelerated product development, expansion into new markets, risk mitigation, reduced regulatory delays and improved quality.

 

Reports from our four facilities have been successfully used by our clients in support of marketing authorization and new product approval submissions around the world, including to the European (EMA, ECHA), US (FDA  and EPA) and Japanese  (MHLW and MAFF) regulatory authorities.

 

CiToxLAB is committed to the humane treatment of the research animals entrusted to our care.  We guarantee they will be treated with the highest standards of respect and compassion, and particular attention is given to housing conditions, social interaction and enrichment of their environment.

 

CiToxLAB‘s Ethics Committees have established and rigorously enforce our Ethics Charter for Laboratory Animals.  All employees must continuously demonstrate their commitment to animal welfare and are required to sign our Ethics Charter as a condition of initial and continuing employment.

 

Since 2004, our high ethical standards have been recognized by accreditation from the American Association of Laboratory Animal Care (AAALAC).

 

As a highly qualified service provider, we also strive to be flexible, accommodating and respond as quickly as possible to each of your individual needs.

Services provided

 

The CiToxLAB Group offers a comprehensive range of pre-clinical services to meet the needs of pharmaceutical, biotechnology and chemical companies worldwide.

 

CiToxLAB carries out studies in general and reproductive toxicology, carcinogenicity, bioanalysis, immunology and safety pharmacology. The group has special expertise in areas such as inhalation or intra-nasal toxicology, radiation safety (ARS), NHPs and minipigs. Environmental studies are a further specialty including ecotoxicology and those related to REACH regulations.

 

CiToxLAB also provides services such as clinical bioanalysis, embryonic stem cell biomarker discovery and customized preclinical efficacy models.

Quality labels and accreditations

GLP, AAALAC, REACH & CLP, ISO 10993

Training and Staff possibilities
No
Contact information
Name
Vibeke
Surname
Dalhoff
Function
Business Development Manager
Phone number
+45 56 86 15 00
Email address
vda@dk.citoxlab.com
Address
Hestehavevej 36A
4623  Ejby, Lille Skensved
Denmark