Database

ALGENICS

Solution provided
Technology
Supplier identity
General description

ALGENICS is a biopharmaceutical company leveraging a unique microalgae-based technology to produce recombinant therapeutics for animal and human health.

Microalgal cell lines engineered using our platform AlgebiosysTM are available under licensing agreement for production of glycosylated therapeutics with preferential applications in the field of monoclonal antibodies and viral subunits.

 

Type of Supplier
Biotechnology Company - Therapeutics
Sector of activity
  • Cancer / Oncology
  • Infectious diseases
  • Protein Therapeutics
  • Vaccines
  • Virology
Region
Regions of Pays de la Loire, Centre and Poitou-Charentes, FR
Regional access broker
  • Grégory Bauer, Atlanpole Biotherapies
Activity description
The 3 top equipments available

Algebiosys™: Algenics Biomanufacturing System

Our company has been founded on several years of biotechnological research on microalgae. We have screened through the genetic diversity of these microorganisms to identify eukaryotic strains with high protein production capacity and for their therapeutic applications.

We have taken advantages of specific biological features of the diatom Phaeodactylum tricornutum to select and engineer our PTA cell line. Our proprietary platform Algebiosys™ encompasses tools and technologies specifically developed to ensure both stable genetic transformation of our cell line and high expression level of recombinant proteins based on proprietary vectors and genetic regulatory elements.

Our technological expertise is currently focused upon the production of 3 major classes of biotherapeutics:

•  Monoclonal antibodies
•  Viral envelope glycoproteins
•  Enzymes for replacement therapy in lysosomal storage diseases

Our technology offers key competitive advantages for biomanufacturing of recombinant therapeutics:

Enable production of complex proteins, including post-translationally modified and multimeric biotherapeutics
Proprietary system for production of biotherapeutics bearing naturally low fucose glycans
Proprietary system for production of biotherapeutics with terminal mannose glycans
High quality and homogeneity of N-glycosylation to improve batch-to-batch consistency
Biotherapeutics products in-process can be secreted into the culture broth or stored within the PTA cells to achieve high amount of encapsulated product.

Our PTA cell line is ‘generally recognized as safe’ (GRAS) and regularly tested for biosafety. We use exclusively culture media free from animal-derived components in single-use bioreactors thereby contributing to a higher safety standard over mammalian and viral expression systems. Furthermore, our strategy is to work closely to adapt our Algebiosys™ expression system to existing technology in upstream and downstream processes.

As a leading technology innovator in microalgae-based expression systems, Algenics provides access to our proprietary technology to enable design around patented manufacturing processes.

Training and Staff possibilities
No
Contact information
Name
LEJEUNE
Surname
Alexandre
Function
Business Development Manager
Phone number
+33 (0)2 40 40 75 22
Address
Pôle BIOOUEST
Rue du Moulin de la Rousselière
44800  SAINT-HERBLAIN
France